INnovative data Science to Impact the TB Epidemic - INSITE
The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).
Funding Fogarty Program
Data Science for Health Discovery and Innovation in Africa (DS-I Africa)
Project Information in NIH RePORTER
INnovative data Science to Impact the TB Epidemic - INSITE
Principal Institution
University of Cape Town
Principal Investigator(s) (PI)
Kalk, Emma Kate
Project Contact Information
Email:
emma.kalk@uct.ac.za
Year(s) Awarded
2023–2026
Country
South Africa
Collaborators
Health Intelligence Directorate of the Western Cape Government
NIH Partners
OD/NIH
Project Description
New drugs and shortened combination regimens have been introduced for the prevention and treatment of drug- susceptible and drug-resistant tuberculosis (TB) but their impact on pregnant people and their infants, including TB transmission and pediatric TB, is uncertain.
This partnership between the Centre for Infectious Disease Epidemiology & Research, University of Cape Town, and the Western Cape Health Intelligence Directorate will consolidate existing relationships across clinical, epidemiological and data science disciplines to establish a scalable data infrastructure for the management of maternal TB at the regional and individual clinical levels.
Data science techniques will be employed to develop and enhance a novel and robust public service population-level data harmonization platform to i) create actionable clinical tools to optimize person-level interventions and monitor programs; ii) generate large, linked cohorts to address epidemiological questions and assess the impact of policy interventions and clinical tools at the population and individual levels.
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