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Salt taste sensitivity, genetics and salt sensitivity of blood pressure in HIV

The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).

Funding Fogarty Program

HIV-associated Noncommunicable Diseases Research at LMIC Institutions

Project Information in NIH RePORTER

Salt taste sensitivity, genetics and salt sensitivity of blood pressure in HIV

Principal Institution

Vanderbilt University Medical Center

Principal Investigator(s) (PI)

Kirabo, Annet; Masenga, Sepiso Kenias

Project Contact Information

Email: annet.kirabo@vanderbilt.edu

Year(s) Awarded

2023-2025

Country

Zambia

NIH Partners

NIDDK

Project Description

Salt taste sensitivity is a driver of salt intake and therefore likely to increase the risk of developing hypertension,  especially among people living with HIV in whom the risk is heightened. Genetic association studies in this area are limited with more research needed in populations of different ethnic backgrounds, such as African populations. The goal of this study is to explore the link between salt taste sensitivity and salt intake, blood pressure, hypertension and genetic variations in the taste receptor gene of ENaC in individuals of African descent.

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