The Impact of Antimalarials and Insecticide Resistance on Malaria Transmission in Uganda
The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).
Funding Fogarty Program
International Research Scientist Development Award (IRSDA)
Project Information in NIH RePORTER
The Impact of Antimalarials and Insecticide Resistance on Malaria Transmission in Uganda
Principal Institution
University of California San Francisco
Principal Investigator(s) (PI)
Conrad, Melissa D
Project Contact Information
Email: melissa.conrad@ucsf.edu
Year(s) Awarded
2018-2023
Country
Uganda
Collaborators
Makerere University
Project Description
The goal of this project is to use our well established clinical and entomological infrastructure in Uganda to perform experiments in which we feed mosquito vectors malaria-infected blood from Ugandan patients using membrane feeding assays. We will measure parasite and mosquito factors that we hypothesize impact on transmission, and use modeling techniques to determine how they influence the number of mosquitoes that become infected and the number of parasites that infect each mosquito. These data and the models that fit them will be useful for helping policy makers decide which interventions to prioritize to reduce the malaria burden in this resource limited settings.
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