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Home > News > Global Health Matters > November / December 2020 Global Health Matters Newsletter > Focus on One Health research: a holistic approach to improving the health of people, animals and the environment Print

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One Health: a holistic approach to improving the health of people, animals and the environment

November / December 2020 | Volume 19, Number 6

Researcher in mask collects sample from camel while others help restrain it in a large field, other camels in background.
Photo courtesy of NIAID

Spillover events, where diseases jump from animals to
humans, are increasing in frequency. Humans have acquired
MERS coronavirus through close contact with camels.

Researchers may never discover exactly how the current novel coronavirus outbreak began, but they agree that as humans have changed the way they interact with animals and the environment, emerging infectious diseases are rapidly growing in frequency. Accelerating rates of deforestation, human settlements encroaching on forests, global trade and travel, and livestock production are thought to be the underlying drivers of so-called “spillover” events, when diseases jump from animals to humans. For example, bats are one of the species suspected to be the source of the virus that causes COVID-19, while viruses in bats and other animals spurred the Ebola outbreak that began in 2014, MERS in 2012 and SARS in 2002, and others. Constant mutations jeopardize existing vaccines and treatments.

With 70% of emerging infectious diseases originating in animals, there is increasing urgency to prioritize the study of zoonotic diseases. “To anticipate threats for humans, we’ve got to partner with people in other disciplines including animal and environmental health,” said Dr. Gregory Gray, a Fogarty grantee and epidemiologist at Duke University.

The One Health movement aims to integrate the efforts of multiple disciplines to improve health for people, animals and the environment. It has become a global effort, including annual conferences that bring scientists and policymakers together to consider how to control existing and emerging infectious diseases. Since the majority of diseases that occur in humans also affect animals, it's important that the biomedical research workforce includes multidisciplinary practitioners with a broad understanding of subjects such as animal anatomy, physiology, pharmacology, epidemiology, behavior science and infectious diseases. Communication strategies and public outreach are also critical to develop interventions such as educational programs for workers to improve hygiene and increase use of personal protective equipment, development of rapid diagnostics and vaccines, and improved food safety measures.

NIH’s zoonotic research is based at Rocky Mountain Laboratories in Montana. Part of the National Institute of Allergy and Infectious Diseases, it’s a state-of-the-art biomedical facility designed for investigations of highly pathogenic viruses. Fogarty supports studies of emerging global threats through its Ecology and Evolution of Infectious Diseases program, a partnership with the National Science Foundation. The initiative supports efforts to understand the underlying ecological and biological mechanisms that govern relationships between environmental changes and the emergence and transmission of infectious diseases. Funded researchers explore how environmental events such as habitat alteration, biological invasion, climate change and pollution alter the risks of disease outbreaks in both animals and humans.

As outbreaks of emerging infectious diseases - such as the current COVID-19 pandemic - increase in frequency and impact, scientists and policymakers are calling for an increased emphasis on global preparedness.

More Information

Resources and publications related to the article Prawn farming reduces disease, provides food source in Senegal:

Resources and publications related to the article Scientists in Tanzania show bacterial zoonoses, not malaria, often the cause of febrile diseases:

Resources and publications related to the article Research improves health among Mongolian livestock herders:

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