Early life aflatoxin B1 exposure and epigenetic programming in Nigerian Newborns
The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).
Funding Fogarty Program
Emerging Global Leader
Project Information in NIH RePORTER
Early life aflatoxin B1 exposure and epigenetic programming in Nigerian Newborns
Principal Institution
Covenant University
Principal Investigator(s) (PI)
Rotimi, Oluwakemi Anuoluwapo
Project Contact Information
Email:
kemi.rotimi@covenantuniversity.edu.ng
Year(s) Awarded
2022–2027
Country
Nigeria
NIH Partners
NCI
Project Description
Aflatoxin B1 (AFB1) is a liver carcinogen that is a common contaminant of foods in sub-Saharan Africa where exposure starts very early in life during pregnancy. This study aims to find out if early-life AFB1 exposure is associated with altered regulation of tumor suppressor genes in Nigerian newborns. The findings of this research could provide an understanding of how early-in-life AFB1 exposure increases the risk of early-onset liver cancer.
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