Pericoronary Adipose Tissue, Inflammation, and Subclinical Coronary Artery Disease in People with HIV in Uganda
The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).
Funding Fogarty Program
Emerging Global Leader
Project Information in NIH RePORTER
Pericoronary Adipose Tissue, Inflammation, and Subclinical Coronary Artery Disease in People with HIV in Uganda
Principal Institution
Mbarara University of Science and Technology
Principal Investigator(s) (PI)
Bibangambah, Prossy Kyasimire
Project Contact Information
Email:
pbibangambah@must.ac.ug
Year(s) Awarded
2024-2029
Country
Uganda
NIH Partners
NHLBI
Project Description
People with HIV (PWH) are at increased risk of developing coronary artery disease (CAD) due to an accelerated inflammatory process resulting in formation of noncalcified plaques, not easily detected by standardized diagnostic methods. Pericoronary adipose tissue (PCAT) may serve as a feasible alternative imaging technique for early detection of coronary inflammation and CAD in people with HIV (PWH). This project will leverage data from two established cohorts to determine relationships between HIV-related inflammation, PCAT, and subclinical CAD among PWH in Uganda.
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