Investigation of responses to Mycobacterium tuberculosis complex lineages by different African host population: Implications for host-directed therapies
The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).
Funding Fogarty Program
Emerging Global Leader
Project Information in NIH RePORTER
Investigation of responses to Mycobacterium tuberculosis complex lineages by different African host population: Implications for host-directed therapies
Principal Institution
Medical Research Labs - Gambia
Principal Investigator(s) (PI)
Tientcheu Djomkam, Leopold
Project Contact Information
Email: tientcheuleo@gmail.com
Year(s) Awarded
2018–2023
Country
Gambia
Collaborators
Emory University
Project Description
The overall aim of this project is to inform the development of host-directed therapeutics for tuberculosis (TB) in Africa where there is epidemiological evidence of differences in disease pattern, bacterial strains and human genetic diversity affecting the outcome of treatment. The results generated from the two African TB-endemic regions will improve our understanding of how new immunomodulatory molecules will work and propose novel host targets for host-directed therapies (HDT) accounting for existing human and bacterial population diversity.
Related World Regions / Countries
Related Global Health Research Topics