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Etiological Role of Parasitic Exposure and Familial Susceptibility in Nodding Syndrome-Related Epilepsies

The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).

Funding Fogarty Program

International Research Scientist Development Award (IRSDA)

Project Information in NIH RePORTER

Etiological Role of Parasitic Exposure and Familial Susceptibility in Nodding Syndrome-Related Epilepsies

Principal Institution

University of California Los Angeles

Principal Investigator(s) (PI)

Mazumder, Rajarshi

Project Contact Information

Email: rmazumder@mednet.ucla.edu

Year(s) Awarded

2022–2027

Country

Regional - Sub-Saharan Africa

Project Description

Despite the high burden of epilepsies in sub-Saharan Africa, many commonly occurring epilepsies remain understudied and poorly characterized. This project focuses on improving our understanding of the role of host genetics and its relationship to exposure to Onchocerca volvulus, a commonly occurring parasite, in the manifestation of epilepsy. Advances from these studies will provide mechanistic insights into epileptogenesis of acquired epilepsies and new targets for developing preventive measures.

Related World Regions / Countries

Related Global Health Research Topics